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GLPrellief supplement bottle and packaging on a marble surface with a green background

Every ingredient, every reason — what's inside GLPrelief, and why a physician chose it.

What's inside matters

Every ingredient chosen for a reason.

15 physician-selected ingredients — active-form vitamins, targeted botanicals, balanced electrolytes, and gentle fiber — formulated by a doctor with 45 years in medical weight loss specifically for people on GLP-1 medications.*

See Supplement Facts
Ginger Root Extract
Ginger Root Extract
Ginger Root Extract
Standardized to 5% gingerols — active gingerol compounds in every serving.
Supports stomach comfort.*
Learn more
L-Theanine
L-Theanine
L-Theanine
Clinical study dose range for calm focus and stress response.
Supports relaxed alertness.*
Learn more
Rhodiola Rosea
Rhodiola Rosea
Rhodiola Rosea Root Extract
Standardized to 3% salidrosides — adaptogenic energy support.
Supports natural energy metabolism.*
Learn more
Chamomile Flower Extract
Chamomile Flower Extract
Chamomile Flower Extract
10:1 concentration — traditionally used for digestive comfort.
Supports digestive comfort and calm.*
Learn more
Vitamin B6 as P5P
Vitamin B6 (P5P)
Vitamin B6 as P5P
30mg active coenzyme form — no liver conversion required.
Supports cellular energy metabolism.*
Learn more
B12 Methylcobalamin
B12 Methylcobalamin
B12 Methylcobalamin
1000mcg active, body-ready form — not synthetic cyanocobalamin.
Supports energy and nervous system.*
Learn more
B2 Riboflavin-5-Phosphate
B2 Riboflavin-5-P
B2 Riboflavin-5-Phosphate
5mg active coenzyme form — drives FAD and FMN cofactors.
Supports cellular energy metabolism.*
Learn more
Thiamin B1
Thiamin (B1)
Thiamin (B1)
25mg as Thiamine Mononitrate.
Supports energy metabolism.*
Learn more
Niacin B3
Niacin (B3)
Niacin (B3)
20mg as Niacinamide — flush-free form.
Supports cellular energy metabolism.*
Learn more
Pantothenic Acid B5
Pantothenic Acid (B5)
Pantothenic Acid (B5)
11mg as D-Calcium Pantothenate — essential for Coenzyme A.
Supports energy metabolism.*
Learn more
Magnesium Malate
Magnesium Malate
Magnesium Malate
150mg — gentle, well-absorbed form. Not oxide.
Supports muscle function and energy.*
Learn more
Sodium
Sodium
Sodium
200mg from sea salt.
Supports electrolyte balance.*
Learn more
Potassium
Potassium
Potassium
99mg — FDA maximum per serving.
Supports muscle function and balance.*
Learn more
Chloride
Chloride
Chloride
420mg from sea salt and potassium chloride.
Supports fluid balance.*
Learn more
Resistant Dextrin
Resistant Dextrin
Resistant Dextrin
1g soluble tapioca fiber — chosen over inulin for GI tolerance.
Gentle prebiotic fiber support.*
Learn more
Free of
Harsh Laxative Minerals
High-Dose Caffeine
Bloat-Inducing Fibers
Artificial Colors or Dyes
Magnesium Oxide
GLPrelief is
Physician-formulated by a doctor with 45 years in medical weight management
Manufactured in a FDA-registered, cGMP-certified U.S. facility
Third-party tested for purity and potency
GRAS ingredients only — Generally Recognized as Safe
Evidence-Based Formulary

75+ ingredients evaluated. 15 made the cut.

GLPrelief wasn't assembled from a catalog. It was developed through a documented ingredient-screening process — the same evidence-based approach used in clinical formulary development — evaluating each candidate against a defined set of criteria before it earned a place in the formula.

Peer-reviewed evidence supporting the ingredient's traditional or clinical use
GRAS status — Generally Recognized as Safe by the FDA
No known contraindications with common co-prescribed medications — statins, antihypertensives, metformin
GI tolerability — every ingredient screened for digestive gentleness in a sensitive population
Bioavailable form — active coenzyme forms where available, standardized extracts where applicable
No subtherapeutic inclusion — if the dose couldn't be meaningful, the ingredient was excluded
Dr. Carroll
George W. Carroll, MD
45 years in medical weight management · 10,000+ patients
Our safety and testing standards
Dr. George W. Carroll, MD — developed GLPrelief through an evidence-based ingredient screening process
Active-Form Vitamins & Minerals

Body-ready. No conversion required.

Vitamin B6 as P5P
VitaminsVitamin B6 as P5P30mg — active coenzyme form.Supports cellular energy metabolism.Learn more
Vitamin B12 as Methylcobalamin
VitaminsB12 Methylcobalamin1000mcg — active, body-ready form.Supports cellular energy and nervous system health.Learn more
Vitamin B2 as Riboflavin-5-Phosphate
VitaminsB2 Riboflavin-5-P5mg — active coenzyme form.Supports cellular energy metabolism.Learn more
Magnesium as Magnesium Malate
MineralsMagnesium Malate150mg — gentle, well-absorbed form.Supports muscle function and cellular energy.Learn more
Sodium from Sea Salt
ElectrolytesSodium200mg from sea salt.Supports electrolyte balance and hydration.Learn more
Formulation Philosophy

We chose the forms that actually work.

Most supplements use the cheapest vitamin forms available. GLPrelief uses the body-ready coenzyme forms — no conversion required.

GLPrelief usesPyridoxal-5-PhosphateActive coenzyme form of B6The form that actually functions as a cofactor in 100+ enzymatic reactions. Your body can use it immediately.Body-ready
vs
Most supplements usePyridoxine HClThe cheapest form. Requires liver conversion through multiple enzymatic steps before becoming usable P5P.Requires conversion
GLPrelief usesMethylcobalaminActive, naturally occurring B12Functions directly as a methyl donor in the methylation cycle — essential for energy, DNA repair, and neurological function.Body-ready
vs
Most supplements useCyanocobalaminSynthetic form. Requires multi-step conversion and releases trace amounts of cyanide in the process.Synthetic · Requires conversion
GLPrelief usesRiboflavin-5-PhosphateActive phosphorylated B2The coenzyme form that drives FAD and FMN — key cofactors in hundreds of energy metabolism reactions.Body-ready
vs
Most supplements useRiboflavinStandard form that must be phosphorylated by the body before it can function as a coenzyme.Requires activation
Physician-Selected Botanicals

Purpose-built for your routine.

Every botanical was chosen for form, quality, and purpose — by a physician with 45 years of medical weight loss experience.

Ginger Root Extract — standardized to 5% gingerols
Botanical · Proprietary BlendGinger Root ExtractStandardized to 5% gingerols — delivering active gingerol compounds in every serving.Supports stomach comfort.*
CO2+water extraction preserves gingerol bioavailability. Verified by HPLC testing at 5.03% total gingerols across 6 compounds.
Learn more
L-Theanine — amino acid for calm focus
Botanical · Proprietary BlendL-TheanineThe same dose range used in clinical studies on calm focus and stress response.Supports relaxed alertness and mental clarity.*
Amino acid found naturally in green tea. Crosses the blood-brain barrier within 30–60 minutes. Promotes alpha brain-wave activity without sedation.
Learn more
Rhodiola Rosea Root Extract — adaptogenic energy support
Botanical · Proprietary BlendRhodiola Rosea Root ExtractStandardized to 3% salidrosides — the bioactive compounds studied for adaptogenic support.Supports natural energy metabolism.*
Adaptogenic herb traditionally used in Scandinavian and Eastern European medicine. Salidroside standardization ensures consistent bioactive potency.
Learn more
Chamomile Flower Extract — digestive comfort and calm
Botanical · Proprietary BlendChamomile Flower Extract10:1 concentration — 10 grams of raw chamomile concentrated into each gram of extract.Supports digestive comfort and a sense of calm.*
Traditionally used for centuries for digestive and nervous system comfort. The 10:1 concentration delivers meaningful botanical compounds in a practical format.
Learn more
The Optimal Formula

Nothing hidden. Everything accounted for.

The supporting B vitamins, electrolytes, and fiber that complete the GLPrelief formula.

B-Vitamin Complex
Thiaminas Thiamine Mononitrate (B1)
25mg
Supports energy metabolism and nervous system function.
Learn more
Niacinas Niacinamide (B3) — flush-free
20mg
Supports cellular energy metabolism. Flush-free form chosen for GLP-1 users.
Learn more
Pantothenic Acidas D-Calcium Pantothenate (B5)
11mg
Essential for Coenzyme A — supports energy metabolism and hormone synthesis.
Learn more
Electrolytes & Fiber
Potassiumas Potassium Chloride
99mg
Supports normal muscle function and electrolyte balance.
Learn more
Chloridefrom sea salt & potassium chloride
420mg
Supports fluid balance and digestive function.
Learn more
Resistant DextrinSoluble Tapioca Fiber
1g
Gentle prebiotic fiber — chosen over inulin specifically for GI tolerance.
Learn more

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Also included

Four balanced electrolytes.

Not one. Not two. A complete profile — sodium, potassium, chloride, and magnesium — working together to support normal hydration and fluid balance.*

Physician-selected balance
200mg
Sodium
from sea salt
99mg
Potassium
FDA max per serving
420mg
Chloride
fluid balance
150mg
Magnesium
as Magnesium Malate

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The GLPrelief standard

What we deliberately left out.

Your digestive system is already adapting. The last thing you need is a supplement that adds to the friction.

Inulin & FOS Fibers
Bloat-inducing fibers
Cheap prebiotic fibers found in most gut supplements. Low cost, high bloat. Known to cause bloating, gas, and cramping — the exact symptoms GLP-1 users are managing.
We use Resistant Dextrin (soluble tapioca fiber) — gentle, non-fermentable.
Magnesium Oxide
Harsh laxative mineral
The cheapest magnesium form in the majority of drugstore supplements. Poorly absorbed and widely known to cause GI distress. The wrong form for a sensitive population.
We use Magnesium Malate — gentle absorption, no laxative effect.
High-Dose Caffeine
Aggressive stimulant
Quick energy boost marketed as "metabolism support." Stimulants on an empty stomach cause jitteriness, acid reflux, and anxiety — common GLP-1 concerns already.
We use Rhodiola Rosea + L-Theanine — calm energy, zero stimulants.
Cyanocobalamin (B12)
Synthetic vitamin form
The cheapest synthetic B12. Requires your body to remove a cyanide molecule and then convert it before use. We chose the active form instead.
We use Methylcobalamin — active, body-ready B12.
Pyridoxine HCl (B6)
Inactive vitamin form
Standard synthetic B6 found in nearly every multivitamin. Requires liver conversion through multiple enzymatic steps before becoming usable P5P.
We use P5P — the active coenzyme form of B6.
Artificial Colors & Dyes
Unnecessary additives
Make products look vibrant and appealing at zero cost. No functional value. Unnecessary chemical exposure for a population already concerned about what goes into their body.
Natural tropical flavor. No artificial colors, dyes, or coloring agents.
Questions

About our formula

We use both plant-derived botanicals and pharmaceutical-grade vitamin forms selected for quality, purity, and bioavailability. Every ingredient is GRAS (Generally Recognized as Safe) and manufactured in a cGMP-certified U.S. facility.

Standard B vitamins (like pyridoxine and cyanocobalamin) require your liver to convert them into usable forms before your cells can use them. GLPrelief uses the already-active coenzyme forms — P5P, Methylcobalamin, and Riboflavin-5-Phosphate — so your body can put them to work directly.

Magnesium Oxide — the cheapest and most common form — is poorly absorbed and known to cause GI distress. Magnesium Malate is significantly gentler on sensitive stomachs and supports both normal muscle function and cellular energy production.

Standardization guarantees a consistent level of the active compound in every serving. Our ginger root extract is tested to contain at least 5% gingerols — the botanical compounds responsible for ginger's soothing properties — delivering active gingerols in every stick pack.

GLPrelief was physician-formulated with the GLP-1 user in mind. All ingredients were selected at doses with established safety profiles. As with any supplement, we recommend discussing GLPrelief with your prescribing physician.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

15 ingredients · 1 stick pack

Every ingredient chosen
for a reason.

Physician-formulated with active-form vitamins, targeted botanicals, balanced electrolytes, and gentle fiber — designed specifically for people on GLP-1 medications.

Physician-Formulated cGMP-Manufactured Third-Party Tested
$59 30-day supply · $1.97/day
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